Articles

Shin, H., Han, J. H., Shin S., Bae, G. H., Son, B., Kim, T. H., Park, H. H., Park, C. G.*, Park, W.* (2024) "M1-polarized macrophage-derived cellular nanovesicle-coated lipid nanoparticles for enhanced cancer treatment through hybridization of gene therapy and cancer immunotherapy", Acta Pharmaceutica Sinica B, Accepted

Son, B.¹, Park, S.¹, Cho, S., Kim, J. A., Baek, S. H., Yoo, K. H., Han, D., Joo, J., Park, H. H.*, Park, T. H.* (2024) "Improved neural inductivity of size-controlled 3D human embryonic stem cells using magnetic nanoparticles", Biomaterials Research, 28,0011 (IF 11.3, JCR 상위 5%)

* Corresponding author

Byun, M. J., Seo, H. S., Lee, J., Ban, K., Oh, S., Lee, Y. Y., Lim, J., Lee, N. K., Wang, C. P., Kim, M., Han, J. H., Park, J., Paik, T., Park, H. H., Park, T. E., Park, W., Kim, S. N.*, Park, D. H.*, Park, C. G.* (2023) "Biofunctional inorganic layered double hydroxide nanohybrid enhances immunotherapeutic effect on atopic dermatitis treatment", Small, 2304862, 1-12 (IF 15.153, JCR 상위 6%)

Son, B.¹, Kim, M.¹, Won, H.¹, Jung, A., Kim, J., Koo, Y., Lee, N. K., Baek, S. H., Han, U., Park, C. G., Shin, H., Gwon, B.*, Joo, J.*, Park, H. H.* (2023) "Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration", Journal of Nanobiotechnology, 21, 1, 1-18 (IF 9.4, JCR 상위 5%)

* Corresponding author

Lee, H.¹, Park, G.¹, Kim, S., Son, B., Joo, J., Park, H. H.*, Park, T. H.* (2022) "Enhancement of anti-tumor activity in melanoma using arginine deiminase fused with 30Kc19α protein", Applied Microbiology and Biotechnology, 106, 22, 7531-7545 (IF 6.355, JCR 상위 15%)

* Corresponding author

Ryu, J.¹, Yang, S. J.¹, Son, B., Lee, H., Lee, J., Joo, J., Park, H. H.*, Park, T. H.* (2022) "Enhanced anti-cancer effect using MMP-responsive L-asparaginase fused with cell-penetrating 30Kc19 protein", Artificial Cells Nanomedicine and Biotechnology, 50, 1, 278-285  (IF 6.355,  JCR 상위 15%)

* Corresponding author

Yoo, J.¹, Kim, K.¹, Kim, S., Park, H. H.*, Shin, H.*, Joo, J.* (2022) "Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery", Nanoscale, 14(39), 14482-14490 (IF 8.307, JCR 상위 15%)

* Corresponding author

Son, B.¹, Yoon, H.¹, Ryu, J., Lee, H., Joo, J., Park, H. H.*, Park, T. H.* (2022) "Enhanced efficiency of generating human induced pluripotent stem cells using Lin28-30Kc19 fusion protein", Frontiers in Bioengineering and Biotechnology, 10 (IF 6.064, JCR 상위 10%)

* Corresponding author

Lee, G.¹, Kim, S. J.¹, , Kim, E. M., Kim, E., Lee, S., Lee, E., Park, H. H.*, Shin, H.* (2022) "Free radical-scavenging composite gelatin methacryloyl hydrogels for cell encapsulation", Acta Biomaterialia, 149, 96-110 (IF 10.633, JCR 상위 10%)

* Corresponding author

Kim, H.¹, Son, B. R.¹, Seo, E. U.¹, Kwon, M., Ahn, J. H., Shin, H., Song, G. Y., Park, E. J., Na, D. H., Cho, S. W., Kim, H. N.*, Park, H. H.*, Lee, W.* (2022) "Cleavage-responsive biofactory T cells suppress infectious diseases-associated hypercytokinemia", Advanced Science, 9, 26 (IF 17.521, JCR 상위 5%)

* Corresponding author

Son, B.¹, Lee, S. H.¹, Hong, S., Kwon, M., Joo, J., Lim, K. S.*, Park, H. H.* (2022) "Direct conversion of bovine dermal fibroblasts into myotubes by viral delivery of transcription factor bMyoD", Applied Sciences, 12, 9

* Corresponding author

Yoo, W.¹, Lee, W.¹ , Kim, H. N.¹, Jeong, J.¹, Park, H. H., Jung, D., Ahn, J. H., Lee, J., Kim, J., Lee, S. W.*, Cho, W. S.*, Kim, S.* (2022) "Nanodiamond as a cytokine sponge in infectious diseases", Frontiers in Bioengineering and Biotechnology, 504

Wang, C. P., Byun, M. J., Kim, S. N., Park, W., Park, H. H., Kim, T. H., Lee, J. S., Park, C. G.* (2022) "Biomaterials as therapeutic drug carriers for inflammatory bowel disease treatment", Journal of Controlled Release, 345, 1-19

Kim, E. M., Lee, G. M., Lee, S., Kim, S., Lee, D., Yoon, D. S., Joo, J., Kong, H., Park, H. H.*, Shin, H.* (2022) "Effects of mechanical properties of gelatin methacryloyl hydrogels on encapsulated stem cell spheroids for 3D tissue engineering", International Journal of Biological Macromolecules, 194, 903-913 (IF 6.953, JCR 상위 10%)

* Corresponding author

Kang, M.¹, Lee, S.H.¹, Kwon, M., Byun, J., Kim, D., Kim, C., Koo, S., Kwon, S. P., Moon, S., Jung, M., Hong, J., Go, S., Song, S. Y., Choi, J. H., Hyeon, T., Oh, Y.K., Park, H. H.*, Kim, B. S.* (2021) "Nanocomplex-mediated in vivo programming to chimeric antigen receptor-M1 macrophages for cancer therapy", Advanced Materials, 33(43) (IF 30.849, JCR 상위 3%)

* Corresponding author

Jeong, H.¹, Kim, W.¹, Choi, D., Heo, J., Han, U., Jung, S. Y., Park, H. H., Hong, S. T., Park, J. H.*, Hong, J.* (2021) "Potential threats of nanoplastic accumulation in human induced pluripotent stem cells", Chemical Engineering Journal, 427, 131841

Choi, K., Lee, S. H., Kwon, M., Hong, S., Park, H. H., Lim, K. S.* (2021) "Development of Anticancer Chemotherapy: Inhibitors of Topoisomerase, HSP90, mTOR and Tyrosine Kinase", KSBB Journal, 36, 2, 99-117

Kim, H.¹, Lee, H.¹, Ahn, J. H.¹, An, J., Hong, K. S., Jang, J. G., An, J., Mun, Y. H., Yoo, S. Y., Choi, Y. J., Yun, M. Y., Song, G. Y., Joo, J., Na, D. H.*, Kim, H. N.*, Park, H. H.*, Lee, J. Y.*, Lee, W.* (2021) "Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm", Nano Today, 38, 101149 (IF 20.722, JCR 상위 5%)

* Corresponding author

Heo, J.¹, Choi, J.¹, Kim, J. Y., Jeong, H., Choi, D., Han, U., Park, J. H., Park, H. H.*, Hong, J.* (2021) "2D graphene oxide particles induce unwanted loss in pluripotency and trigger early differentiation in human pluripotent stem cells", Journal of Hazardous Materials, 414, 125472 (IF 10.588, JCR 상위 3%)

* Corresponding author

Park, H. H.¹, Kim, H.¹, Lee, H.¹, Seo, E. U.¹, Kim, J. E.¹, Lee, J. H., Mun, Y. H., Yoo, S. Y., An, J., Yun, M. Y., Kang, N. W., Kim, D. D., Na, D. H., Hong, K. S., Jang, J. G., Ahn, J. H., Bae, J. S.*, Song, G. Y.*, Lee, J. Y.*, Kim, H. N.*, Lee, W.* (2021) "PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses", Biomaterials, 273, 120827 (IF 12.479, JCR 상위 3%)

1 First author

Lee, S., Lee, J., Byun, H., Kim, S., Joo, J., Park, H. H., Shin, H.* (2021) "Evaluation of the anti-oxidative and ROS scavenging properties of biomaterials coated with epigallocatechin gallate for tissue engineering", Acta Biomaterialia, 124, 166-178

Choi, D. W.¹, Roh, Y. J.¹, Kim, S.¹, Lee, H. M., Kim, M., Shin, D., Park, J. H., Park, H. H., Ok, Y. S., Kang, D., Kim, J. H, Tarrago, L., Danial, N. N., Gladyshev, V. N., Min, P. K.*, Lee, B. C.* (2021) "Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues", Biosensors and Bioelectronics, 178, 113031

Lee, Y. Y.¹, Park, H. H.¹, Park, W.¹, Kim, H.¹, Jang, J. G., Hong, K. S., Lee, J. Y., Seo, H. S., Na, D. H., Kim, T. H., Choy, Y. B., Ahn, J. H.*, Lee, W.*, Park, C. G.* (2021) "Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm" Biomaterials, 267, 120389 (IF 10.317, JCR 상위 3%)

1 First author

Cha, H.¹, Hong, S.¹, Park, J. H.*, Park, H. H.* (2020) "Stem cell-derived exosomes and nanovesicles: Promotion of cell proliferation, migration and anti-senescence for treatment of wound damage and skin ageing", Pharmaceutics, 12, 12, 1135

* Corresponding author

Cha, H.¹, Lee, J.¹, Park, H. H.*, Park, J., H.* (2020) "Direct conversion of human fibroblasts into osteoblasts triggered by histone deacetylase inhibitor valproic acid", Applied Sciences, 10, 20, 7372

* Corresponding author

Park, H. H.¹, Park, W.¹, Lee, Y. Y.¹, Kim, H., Seo, H. S., Choi, D. W., Kwon, H. K., Na, D. H., Kim, T. H., Choy, Y. B., Ahn, J. H.*, Lee, W.*, Park, C. G.* (2020) "Bioinspired DNase-I-coated melanin-like nanospheres for modulation of infection-associated NETosis dysregulation", Advanced Science, 7, 2001940 (IF 15.840, JCR 상위 5%)

1 First author

Kim, H. N.¹, Park, H. H.¹, Lim, W.¹, Hong, K. S., Ahn, J. H., Na, D. H., Kim, I. S., Jang, J. G.*, Bae, J. S.*, Lee, W.* (2020) "Ferritin nanocage-based methyltransferase SETD6 for COVID-19 therapy", Advanced Functional Materials, 30, 2006110 (IF 16.836, JCR 상위 5%)

1 First author

Lee, H.¹, Kim, S.¹, Yoon, H., Ryu, J., Park, H. H., Hwang, N. S.*, Park, T. H.* (2020) "Intracellular delivery of recombinant RUNX2 facilitated by cell-penetrating protein for the osteogenic differentiation of hMSCs", ACS Biomaterials Science and Engineering, 6, 9, 5202-5214

Lee, W.¹, Ahn, J. H.¹, Park, H. H.¹, Kim, H. N.¹, Kim, H., Yoo, Y., Shin, H., Hong, K. S., Jang, J. G., Park, C. G., Choi, E. Y. *, Bae, J. S.*, Seo, Y. K.* (2020) "COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm", Signal Transduction and Targeted Therapy, 5, 1, 1-11 (IF 13.493, JCR 상위 3%)

1 First author

Choi, E. Y.¹, Park, H. H.¹, Kim, H.¹, Kim, H., N., Kim, I., Jeon, S., Kim, W.*, Bae, J. S.*, Lee, W.* (2020) "Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for SARS-CoV-2 patients", European Respiratory Journal, 56, 5, 2001531 (IF 12.339, JCR 상위 6%)

1 First author

Park, H., Kwon, M., Kwang Suk Lim*, Park, H. H.* (2020) "Chimeric Antigen Receptor-T cell (CAR-T) therapy targeting hematologic malignancy", KSBB Journal, 35, 3, 183-191

* Corresponding author

Park, H. H.¹, Kim, H. N.¹, Kim, H.¹, Yoo, Y., Shin, H., Choi, E. Y. *, Bae, J. S. *, Lee, W.* (2020) "Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia", Science Advances, 6, 31, eabc1564 (IF 13.117, JCR 상위 5%)

1 First author

Yu, H.¹, Hong, S.¹, Kwon, M., Lee, J., Park, H., H., Lim, K. S.* (2020) "Therapeutic antibodies for the treatment of cancer: Cancer Immunotherapy", KSBB Journal, 35, 2, 105-119

Kwon, M., Park, H. H.* (2020) "CAR-T therapy targeting solid tumor", KSBB Journal, 35, 2, 95-104

* Corresponding author

Hong, S.¹, Choi, D. W.¹, Kim, H. N.¹, Park, C. G.*, Lee, W.*, Park, H. H.* (2020) "Protein-based nanoparticles as drug delivery systems", Pharmaceutics, 12, 7, 604

* Corresponding author

Lee, J., Lim, K. S., Park, H. H., Ha, S. J.* (2020) "A qualitative case study on the teaching experiences of biotechnology-related curriculum linked extracurricular program management", The Korean Society of Culture and Convergence, 42, 5, 729-758

Hong, S., Park, H. H.* (2020) "Drug delivery system using protein nanoparticles", KSBB Journal, 35, 1, 10-22

* Corresponding author

Ryu, J., Hwang, N. S., Park, H. H.*, Park, T. H.* (2020) "Protein-based direct reprogramming of fibroblasts to neuronal lineage cells", International Journal of Biochemistry and Cell Biology, 121, 105717

* Corresponding author

Lee, J., Park, H. H., Lim, K. S., Lee, H. J., Ha, S. J.* (2019) "A case study on biotechnology-related curriculum linked extracurricular program - focusing on K university CUBE program", KSBB Journal, 34, 4, 359-365

Lee, J., Park, H. H., Park, J. H.* (2019) "Efficient production of cell-permeable Oct4 protein using silkworm-originating 30Kc19 protein" Biotechnology and Bioprocess Engineering, 24, 6, 1-8

Ryu, J., Park, S. W., Park, H. H.*, Park, T. H.* (2019) "Enhanced single-cell viability using 30Kc6 for efficient expansion of human induced pluripotent stem cells", Process Biochemistry, 78, 161–168

* Corresponding author

Razzak, A., Lee, J. E., Park, H. H., Park, T. H., Choi, S. S.* (2018) "Exploring binding mechanisms between curcumin and silkworm 30Kc19 protein using spectroscopic analyses and computational simulations", Biotechnology and Bioprocess Engineering, 5, 23, 605-616

Park, H. H., Triboulet, R., Bentler, M., Guda, S., Du, P., Xu, H., Gregory, R. I., Brendel, C., Williams, D. A.* (2018) "DROSHA knockout leads to enhancement of viral titers for vectors encoding miRNA-adapted shRNAs", Molecular Therapy-Nucleic Acids, 12, 591-599 (IF 7.367, JCR 상위 10%)

First author

Park, H. H.¹, Woo, W. H.¹, Ryu, J., Lee, H. J., Park, J. H.*, Park, T. H.* (2017) "Enzyme delivery using protein-stabilizing and cell-penetrating 30Kc19α protein nanoparticles", Process Biochemistry, 63, 76-83

1 First author

Han, U.¹, Park, H. H.¹, Kim Y. J. Park, T. H., Park, J. H.*, Hong, J.* (2017) "Efficient encapsulation and sustained release of basic fibroblast growth factor in nanofilm: extension of the feeding cycle of human induced pluripotent stem cell culture", ACS Applied Materials and Interfaces, 9, 30, 25087-25097 (IF 8.758, JCR 상위 10%)

1 First author

Choi, M.¹, Park, H. H.¹, Choi, D., Han, U., Park, T. H., Lee, H., Park, J. H., Hong, J.* (2017) "Multilayer nanofilms via inkjet printing for stabilizing growth factor and designing desired cell developments", Advanced Healthcare Materials, 6, 14, 1700216 (IF 7.367, JCR 상위 10%)

1 First author

Ryu, J.¹, Kim, H.¹, Park. H. H., Park, J. H., Lee, H. J., Rhee, W. J., Park, T. H.* (2016) "Protein‐stabilizing and cell‐penetrating properties of α‐helix domain of 30Kc19 protein", Biotechnology Journal, 11, 1443-1451

Lee, H. J.¹, Park, H. H.¹, Sohn, Y., Park, J. H., Ryu, J., Rhee, W. J., Park, T. H.* (2016) "Alpha-galactosidase delivery using 30Kc19-human serum albumin nanoparticles for effective treatment of Fabry disease", Applied Microbiology and Biotechnology, 100, 24, 10395-10402

1 First author

Park, H. H.¹, Choi, J.¹, Lee, H. J., Park, J. H., Ryu, J., Rhee, W. J.*, Park, T. H.* (2015) "Enhancement of human erythropoietin production in Chinese hamster ovary cells through supplementation of 30Kc19-30Kc6 fusion protein", Process Biochemistry, 50, 6, 973-980

1 First author

Ryu, J., Park, H. H., Park, J. H., Lee, H. J., Rhee, W. J., Park, T. H.* (2016) "Soluble expression and stability enhancement of transcription factors using 30Kc19 cell-penetrating protein", Applied Microbiology and Biotechnology, 100, 3523-3532

Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J., Park, T. H.* (2014) "Dimerization of 30Kc19 protein in the presence of amphiphilic moiety and importance of Cys-57 during cell penetration", Biotechnology Journal, 9, 1582-1593

First author

Park, J. H.¹, Lee, H. J.¹, Park, H. H., Rhee, W. J., Park T. H.* (2014) "Stabilization of cellular mitochondrial enzyme complex and sialyltransferase activity through supplementation of 30Kc19 protein", Applied Microbiology and Biotechnology, 99, 2155-2163

Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J.*, Park, T. H.* (2014) "Identification and characterization of a novel cell-penetrating peptide of 30Kc19 protein derived from Bombyx mori", Process Biochemistry, 49, 1516-1526

First author

Lee, H. J., Park, H. H., Kim, J. A., Park, J. H., Ryu, J., Choi, J., Lee, J., Rhee, W. J., Park, T. H.* (2014) "Enzyme delivery using the 30Kc19 protein and human serum albumin nanoparticles", Biomaterials, 35, 1696-1704

Lee, S. H., Rhee, H. -W., Van Noort, D., Lee, H. J., Park, H. H., Shin, I. -S., Hong, J. -I.*, Park, T. H.* (2014) "Microfluidic bead-based sensing platform for monitoring kinase activity", Biosensors and Bioelectronics, 57, 1-9

Park, J. H., Park, H. H., Choi, S. S., Park, T. H.* (2012) "Stabilization of enzymes by the recombinant 30Kc19 protein", Process Biochemistry, 47, 164-169

Park, J. H., Lee, J. H., Park, H. H., Rhee, W. J., Choi, S. S.*, Park, T. H.* (2012) "A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm”, Biomaterials, 33, 9127-9134

Park, J. H., Wang, Z., Jeong, H. -J., Park, H. H., Kim, B. -G., Tan, W. -S., Choi, S. S., Park, T. H.* (2012) "Enhancement of recombinant human EPO production and glycosylation in serum-free suspension culture of CHO cells through expression and supplementation of 30Kc19", Applied Microbiology and Biotechnology, 96, 671-683

Wang, Z, Park, J. H., Park, H. H., Tan, W., Park, T. H.* (2011) "Enhancement of recombinant human EPO production and sialylation in Chinese hamster ovary cells through Bombyx mori 30Kc19 gene expression", Biotechnology and Bioengineering, 108, 1634-1642

Wang, Z, Park, J. H., Park, H. H., Tan, W., Park, T. H.* (2010) "Enhancement of therapeutic monoclonal antibody production in CHO cells using 30Kc6 gene" Process Biochemistry, 45(12), 1852-1856

Park, J. H., Park, H. H., Park, T. H.* (2010) "Cellular engineering for the high-level production of recombinant proteins in mammalian cell systems" Korean Journal of Chemical Engineering, 27(4), 1042-1048

Koo, T. Y., Park, J. H., Park, H. H., Park, T. H.* (2009) "Beneficial effect of 30Kc6 gene expression on production of recombinant interferon-β in serum-free suspension culture of CHO cells" Process Biochemistry, 44(2), 146-153

Oh, J. S., Park, H. H., Park, T. H.* (2008) "Temperature management strategy for efficient gene expression in a thermally inducible Escherichia coil/bacteriophage system" Biotechnology. and Bioprocess Engineering., 13, 470-475