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Articles

53. Son, B.1, Lee, S. H.1, Hong, S., Kwon, M., Joo, J., Lim, K. S.*, Park, H.H.* (2022) "Direct conversion of bovine dermal fibroblasts into myotubes by viral delivery of transcription factor bMyoD", Applied Sciences, Accepted

* Co-corresponding author

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52. Yoo, W.1, Lee, W.1 , Kim, H. N.1, Jeong, J.1, Park, H. H., Jung, D., Ahn, J. H., Lee, J., Kim, J., Lee, S. W.*, Cho, W. S.*, Kim, S.* (2022) "Nanodiamond as a cytokine sponge in infectious diseases", Frontiers in Bioengineering and Biotechnology, 504

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51. Wang, C. P., Byun, M. J., Kim, S. N., Park, W., Park, H. H., Kim, T. H., Lee, J. S., Park, C. G.*  (2022) "Biomaterials as therapeutic drug carriers for inflammatory bowel disease treatment", Journal of Controlled Release, In Press (IF 9.776, JCR 상위 3%)

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50. Kim, E. M., Lee, G. M., Lee, S., Kim, S., Lee, D., Yoon, D. S., Joo, J., Kong, H., Park, H. H.*, Shin, H.* (2022) "Effects of mechanical properties of gelatin methacryloyl hydrogels on encapsulated stem cell spheroids for 3D tissue engineering", International Journal of Biological Macromolecules, 194, 903-913 (IF 6.953, JCR 상위 10%)
* Co-corresponding author

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49. Kang, M.1, Lee, S.H.1, Kwon, M., Byun, J., Kim, D., Kim, C., Koo, S., Kwon, S. P., Moon, S., Jung, M., Hong, J., Go, S., Song, S. Y., Choi, J. H., Hyeon, T., Oh, Y.K., Park, H. H.*, Kim, B. S.* (2021) "Nanocomplex-mediated in vivo programming to chimeric antigen receptor-M1 macrophages for cancer therapy", Advanced Materials, 2103258 (IF 30.849, JCR 상위 3%)
* Co-corresponding author

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48. Jeong, H.1, Kim, W.1, Choi, D., Heo, J., Han, U., Jung, S. Y., Park, H. H., Hong, S. T., Park, J. H.*, Hong, J.* (2021) "Potential threats of nanoplastic accumulation in human induced pluripotent stem cells", Chemical Engineering Journal, 427, 131841

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47. Choi, K., Lee, S. H., Kwon, M., Hong, S., Park, H. H., Lim, K. S.* (2021) "Development of Anticancer Chemotherapy: Inhibitors of Topoisomerase, HSP90, mTOR and Tyrosine Kinase", KSBB Journal, 36, 2, 99-117

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46. Kim, H.1, Lee, H.1, Ahn, J. H.1, An, J., Hong, K. S., Jang, J. G., An, J., Mun, Y. H., Yoo, S. Y., Choi, Y. J., Yun, M. Y., Song, G. Y., Joo, J., Na, D. H.*, Kim, H. N.*, Park, H. H.*, Lee, J. Y.*, Lee, W.* (2021) "Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm", Nano Today, 101149 (IF 20.722, JCR 상위 5%)

* Co-corresponding author

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45. Heo, J.1, Choi, J.1, Kim, J. Y., Jeong, H., Choi, D., Han, U., Park, J. H., Park, H. H.*, Hong, J.* (2021) "2D graphene oxide particles induce unwanted loss in pluripotency and trigger early differentiation in human pluripotent stem cells", Journal of Hazardous Materials, 125472 (IF 10.588, JCR 상위 3%)

* Co-corresponding author

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44. Park, H. H.1, Kim, H.1, Lee, H.1, Seo, E. U.1, Kim, J. E.1, Lee, J. H., Mun, Y. H., Yoo, S. Y., An, J., Yun, M. Y., Kang, N. W., Kim, D. D., Na, D. H., Hong, K. S., Jang, J. G., Ahn, J. H., Bae, J. S.*, Song, G. Y.*, Lee, J. Y.*, Kim, H. N.*, Lee, W.* (2021) "PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses", Biomaterials, 120827 (IF 12.479, JCR 상위 3%)

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43. Lee, S., Lee, J., Byun, H., Kim, S., Joo, J., Park, H. H., Shin, H.* (2021) "Evaluation of the anti-oxidative and ROS scavenging properties of biomaterials coated with epigallocatechin gallate for tissue engineering", Acta Biomaterialia, 124, 166-178

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42. Choi, D. W.1, Roh, Y. J.1, Kim, S.1, Lee, H. M., Kim, M., Shin, D., Park, J. H., Park, H. H., Ok, Y. S., Kang, D., Kim, J. H, Tarrago, L., Danial, N. N., Gladyshev, V. N., Min, P. K.*, Lee, B. C.* (2021) "Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues", Biosensors and Bioelectronics, 113031

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41. Lee, Y. Y.1, Park, H. H.1, Park, W.1, Kim, H.1, Jang, J. G., Hong, K. S., Lee, J. Y., Seo, H. S., Na, D. H., Kim, T. H., Choy, Y. B., Ahn, J. H.*, Lee, W.*, Park, C. G.* (2021) "Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm" Biomaterials, 267, 120389 (IF 10.317, JCR 상위 3%)

1 Co-first author

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40. Cha, H.1, Hong, S.1, Park, J. H.*, Park, H. H.* (2020) "Stem cell-derived exosomes and nanovesicles: Promotion of cell proliferation, migration and anti-senescence for treatment of wound damage and skin ageing", Pharmaceutics, 12, 12, 1135

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39. Cha, H.1, Lee, J.1, Park, H. H.*, Park, J., H.* (2020) "Direct conversion of human fibroblasts into osteoblasts triggered by histone deacetylase inhibitor valproic acid", Applied Sciences, 10, 20, 7372

* Co-corresponding author

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38. Park, H. H.1, Park, W.1, Lee, Y. Y.1, Kim, H., Seo, H. S., Choi, D. W., Kwon, H. K., Na, D. H., Kim, T. H., Choy, Y. B., Ahn, J. H.*, Lee, W.*, Park, C. G.* (2020) "Bioinspired DNase-I-coated melanin-like nanospheres for modulation of infection-associated NETosis dysregulation", Advanced Science, 7, 2001940 (IF 15.840, JCR 상위 5%)

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37. Kim, H. N.1, Park, H. H.1, Lim, W.1, Hong, K. S., Ahn, J. H., Na, D. H., Kim, I. S., Jang, J. G.*, Bae, J. S.*, Lee, W.* (2020) "Ferritin nanocage-based methyltransferase SETD6 for COVID-19 therapy", Advanced Functional Materials, 30, 2006110 (IF 16.836, JCR 상위 5%)

1 Co-first author

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36. Lee, H.1, Kim, S.1, Yoon, H., Ryu, J., Park, H. H., Hwang, N. S.*, Park, T. H.* (2020) "Intracellular delivery of recombinant RUNX2 facilitated by cell-penetrating protein for the osteogenic differentiation of hMSCs", ACS Biomaterials Science and Engineering, 6, 9, 5202-5214

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35. Lee, W.1, Ahn, J. H.1, Park, H. H.1, Kim, H. N.1, Kim, H., Yoo, Y., Shin, H., Hong, K. S., Jang, J. G., Park, C. G., Choi, E. Y. *, Bae, J. S.*, Seo, Y. K.* (2020) "COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm", Signal Transduction and Targeted Therapy, 5, 1, 1-11 (IF 13.493, JCR 상위 3%)

1 Co-first author

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34. Choi, E. Y.1, Park, H. H.1, Kim, H.1, Kim, H., N., Kim, I., Jeon, S., Kim, W.*, Bae, J. S.*, Lee, W.* (2020) "Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for SARS-CoV-2 patients", European Respiratory Journal, 56, 5, 2001531 (IF 12.339, JCR 상위 6%)

1 Co-first author

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33. Park, H., Kwon, M., Kwang Suk Lim*, Park, H. H.* (2020) "Chimeric Antigen Receptor-T cell (CAR-T) therapy targeting hematologic malignancy", KSBB Journal, 35, 3, 183-191

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32. Park, H. H.1, Kim, H. N.1, Kim, H.1, Yoo, Y., Shin, H., Choi, E. Y. *, Bae, J. S. *, Lee, W.* (2020) "Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia", Science Advances, 6, 31, eabc1564 (IF 13.117, JCR 상위 5%)

1 Co-first author

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31. Yu, H.1, Hong, S.1, Kwon, M., Lee, J., Park, H., H., Lim, K. S.* (2020) "Therapeutic antibodies for the treatment of cancer: Cancer Immunotherapy", KSBB Journal, 35, 2, 105-119

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30. Kwon, M., Park, H. H.* (2020) "CAR-T therapy targeting solid tumor", KSBB Journal, 35, 2, 95-104

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29. Hong, S.1, Choi, D. W.1, Kim, H. N.1, Park, C. G.*, Lee, W.*, Park, H. H.* (2020) "Protein-based nanoparticles as drug delivery systems", Pharmaceutics, 12, 7, 604

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28. Lee, J., Lim, K. S., Park, H. H., Ha, S. J.* (2020) "A qualitative case study on the teaching experiences of biotechnology-related curriculum linked extracurricular program management", The Korean Society of Culture and Convergence, 42, 5, 729-758

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27. Hong, S., Park, H. H.* (2020) "Drug delivery system using protein nanoparticles", KSBB Journal, 35, 1, 10-22

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26. Ryu, J., Hwang, N. S., Park, H. H.*, Park, T. H.* (2020) "Protein-based direct reprogramming of fibroblasts to neuronal lineage cells", International Journal of Biochemistry and Cell Biology, 121, 105717

* Co-corresponding author

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25. Lee, J., Park, H. H., Lim, K. S., Lee, H. J., Ha, S. J.* (2019) "A case study on biotechnology-related curriculum linked extracurricular program - focusing on K university CUBE program", KSBB Journal, 34, 4, 359-365

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24. Lee, J., Park, H. H., Park, J. H.* (2019) "Efficient production of cell-permeable Oct4 protein using silkworm-originating 30Kc19 protein" Biotechnology and Bioprocess Engineering, 24, 6, 1-8

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23. Ryu, J., Park, S. W., Park, H. H.*, Park, T. H.* (2019) "Enhanced single-cell viability using 30Kc6 for efficient expansion of human induced pluripotent stem cells", Process Biochemistry, 78, 161–168

* Co-corresponding author

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22. Razzak, A., Lee, J. E., Park, H. H., Park, T. H., Choi, S. S.* (2018) "Exploring binding mechanisms between curcumin and silkworm 30Kc19 protein using spectroscopic analyses and computational simulations", Biotechnology and Bioprocess Engineering, 5, 23, 605-616

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21. Park, H. H., Triboulet, R., Bentler, M., Guda, S., Du, P., Xu, H., Gregory, R. I., Brendel, C., Williams, D. A.* (2018) "DROSHA knockout leads to enhancement of viral titers for vectors encoding miRNA-adapted shRNAs", Molecular Therapy-Nucleic Acids, 12, 591-599 (IF 7.367, JCR 상위 10%)

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20. Park, H. H.1, Woo, W. H.1, Ryu, J., Lee, H. J., Park, J. H.*, Park, T. H.* (2017) "Enzyme delivery using protein-stabilizing and cell-penetrating 30Kc19α protein nanoparticles", Process Biochemistry, 63, 76-83

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19. Han, U.1, Park, H. H.1, Kim Y. J. Park, T. H., Park, J. H.*, Hong, J.* (2017) "Efficient encapsulation and sustained release of basic fibroblast growth factor in nanofilm: extension of the feeding cycle of human induced pluripotent stem cell culture", ACS Applied Materials and Interfaces, 9, 30, 25087-25097 (IF 8.758, JCR 상위 10%)

1 Co-first author

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18. Choi, M.1, Park, H. H.1, Choi, D., Han, U., Park, T. H., Lee, H., Park, J. H., Hong, J.* (2017) "Multilayer nanofilms via inkjet printing for stabilizing growth factor and designing desired cell developments", Advanced Healthcare Materials, 6, 14, 1700216 (IF 7.367, JCR 상위 10%)

1 Co-first author

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17. Ryu, J.1, Kim, H.1, Park. H. H., Park, J. H., Lee, H. J., Rhee, W. J., Park, T. H.* (2016) "Protein‐stabilizing and cell‐penetrating properties of α‐helix domain of 30Kc19 protein", Biotechnology Journal, 11, 1443-1451

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16. Lee, H. J.1, Park, H. H.1, Sohn, Y., Park, J. H., Ryu, J., Rhee, W. J., Park, T. H.* (2016) "Alpha-galactosidase delivery using 30Kc19-human serum albumin nanoparticles for effective treatment of Fabry disease", Applied Microbiology and Biotechnology, 100, 24, 10395-10402

1 Co-first author

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15. Park, H. H.1, Choi, J.1, Lee, H. J., Park, J. H., Ryu, J., Rhee, W. J.*, Park, T. H.* (2015) "Enhancement of human erythropoietin production in Chinese hamster ovary cells through supplementation of 30Kc19-30Kc6 fusion protein", Process Biochemistry, 50, 6, 973-980

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14. Ryu, J., Park. H. H., Park, J. H., Lee, H. J., Rhee, W. J., Park, T. H.* (2016) "Soluble expression and stability enhancement of transcription factors using 30Kc19 cell-penetrating protein", Applied Microbiology and Biotechnology, 100, 3523-3532

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13. Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J., Park, T. H.* (2014) "Dimerization of 30Kc19 protein in the presence of amphiphilic moiety and importance of Cys-57 during cell penetration", Biotechnology Journal, 9, 1582-1593

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12. Park, J. H.1, Lee, H. J.1, Park, H. H., Rhee, W. J., Park T. H.* (2014) "Stabilization of cellular mitochondrial enzyme complex and sialyltransferase activity through supplementation of 30Kc19 protein", Applied Microbiology and Biotechnology, 99, 2155-2163

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11. Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J.*, Park, T. H.* (2014) "Identification and characterization of a novel cell-penetrating peptide of 30Kc19 protein derived from Bombyx mori", Process Biochemistry, 49, 1516-1526

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10. Lee, H. J., Park, H. H., Kim, J. A., Park, J. H., Ryu, J., Choi, J., Lee, J., Rhee, W. J., Park, T. H.* (2014) "Enzyme delivery using the 30Kc19 protein and human serum albumin nanoparticles", Biomaterials, 35, 1696-1704

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9. Lee, S. H., Rhee, H. -W., Van Noort, D., Lee, H. J., Park, H. H., Shin, I. -S., Hong, J. -I.*, Park, T. H.* (2014) "Microfluidic bead-based sensing platform for monitoring kinase activity", Biosensors and Bioelectronics, 57, 1-9

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8. Park, J. H., Park, H. H., Choi, S. S., Park, T. H.* (2012) "Stabilization of enzymes by the recombinant 30Kc19 protein", Process Biochemistry, 47, 164-169

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7. Park, J. H., Lee, J. H., Park, H. H., Rhee, W. J., Choi, S. S.*, Park, T. H.* (2012) "A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm”, Biomaterials, 33, 9127-9134

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6. Park, J. H., Wang, Z., Jeong, H. -J., Park, H. H., Kim, B. -G., Tan, W. -S., Choi, S. S., Park, T. H.* (2012) "Enhancement of recombinant human EPO production and glycosylation in serum-free suspension culture of CHO cells through expression and supplementation of 30Kc19", Applied Microbiology and Biotechnology, 96, 671-683

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5. Wang, Z, Park, J. H., Park, H. H., Tan, W., Park, T. H.* (2011) "Enhancement of recombinant human EPO production and sialylation in Chinese hamster ovary cells through Bombyx mori 30Kc19 gene expression", Biotechnology and Bioengineering, 108, 1634-1642

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4. Wang, Z, Park, J. H., Park, H. H., Tan, W., Park, T. H.* (2010) "Enhancement of therapeutic monoclonal antibody production in CHO cells using 30Kc6 gene" Process Biochemistry, 45(12), 1852-1856

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3. Park, J. H., Park, H. H., Park, T. H.* (2010) "Cellular engineering for the high-level production of recombinant proteins in mammalian cell systems" Korean Journal of Chemical Engineering, 27(4), 1042-1048

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2. Koo, T. Y., Park, J. H., Park, H. H., Park, T. H.* (2009) "Beneficial effect of 30Kc6 gene expression on production of recombinant interferon-β in serum-free suspension culture of CHO cells" Process Biochemistry, 44(2), 146-153

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1. Oh, J. S., Park, H. H., Park, T. H.* (2008) "Temperature management strategy for efficient gene expression in a thermally inducible Escherichia coil/bacteriophage system" Biotechnology. and Bioprocess Engineering., 13, 470-475

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