top of page

Articles

57

Yoo, J.1, Kim, K.1, Kim, S., Park, H. H.*, Shin, H.*, Joo, J.* (2022) "Tailored polyethylene glycol grafting on porous nanoparticles for enhanced targeting and intracellular siRNA delivery", Nanoscale, Accepted (IF 8.307, JCR 상위 15%)

* Co-corresponding author

56

Son, B.1, Yoon, H.1, Ryu, J., Lee, H., Joo, J., Park, H.H.*, Park, T. H.* (2022) "Enhanced efficiency of generating human induced pluripotent stem cells using Lin28-30Kc19 fusion protein", Frontiers in Bioengineering and Biotechnology, Accepted (IF 6.064, JCR 상위 10%)

* Co-corresponding author

55

Lee, G.1, Kim, S. J.1, , Kim, E. M., Kim, E., Lee, S., Lee, E., Park, H. H.*, Shin, H.* (2022) "Free radical-scavenging composite gelatin methacryloyl hydrogels for cell encapsulation", Acta Biomaterialia, Accepted (IF 10.633, JCR 상위 10%)

* Co-corresponding author

54

Kim, H.1, Son, B. R.1, Seo, E. U.1, Kwon, M., Ahn, J. H., Shin, H., Song, G. Y., Park, E. J., Na, D. H., Cho, S. W., Kim, H. N.*, Park, H. H.*, Lee, W.* (2022) "Cleavage-responsive biofactory T cells suppress infectious diseases-associated hypercytokinemia", Advanced Science, Accepted (IF 17.521, JCR 상위 5%)

* Co-corresponding author

53

Son, B.1, Lee, S. H.1, Hong, S., Kwon, M., Joo, J., Lim, K. S.*, Park, H.H.* (2022) "Direct conversion of bovine dermal fibroblasts into myotubes by viral delivery of transcription factor bMyoD", Applied Sciences, Accepted

* Co-corresponding author

52

Yoo, W.1, Lee, W.1 , Kim, H. N.1, Jeong, J.1, Park, H. H., Jung, D., Ahn, J. H., Lee, J., Kim, J., Lee, S. W.*, Cho, W. S.*, Kim, S.* (2022) "Nanodiamond as a cytokine sponge in infectious diseases", Frontiers in Bioengineering and Biotechnology, 504

51

Wang, C. P., Byun, M. J., Kim, S. N., Park, W., Park, H. H., Kim, T. H., Lee, J. S., Park, C. G.* (2022) "Biomaterials as therapeutic drug carriers for inflammatory bowel disease treatment", Journal of Controlled Release, In Press

50

Kim, E. M., Lee, G. M., Lee, S., Kim, S., Lee, D., Yoon, D. S., Joo, J., Kong, H., Park, H. H.*, Shin, H.* (2022) "Effects of mechanical properties of gelatin methacryloyl hydrogels on encapsulated stem cell spheroids for 3D tissue engineering", International Journal of Biological Macromolecules, 194, 903-913 (IF 6.953, JCR 상위 10%)
* Co-corresponding author

49

Kang, M.1, Lee, S.H.1, Kwon, M., Byun, J., Kim, D., Kim, C., Koo, S., Kwon, S. P., Moon, S., Jung, M., Hong, J., Go, S., Song, S. Y., Choi, J. H., Hyeon, T., Oh, Y.K., Park, H. H.*, Kim, B. S.* (2021) "Nanocomplex-mediated in vivo programming to chimeric antigen receptor-M1 macrophages for cancer therapy", Advanced Materials, 2103258 (IF 30.849, JCR 상위 3%)
* Co-corresponding author

48

Jeong, H.1, Kim, W.1, Choi, D., Heo, J., Han, U., Jung, S. Y., Park, H. H., Hong, S. T., Park, J. H.*, Hong, J.* (2021) "Potential threats of nanoplastic accumulation in human induced pluripotent stem cells", Chemical Engineering Journal, 427, 131841

47

Choi, K., Lee, S. H., Kwon, M., Hong, S., Park, H. H., Lim, K. S.* (2021) "Development of Anticancer Chemotherapy: Inhibitors of Topoisomerase, HSP90, mTOR and Tyrosine Kinase", KSBB Journal, 36, 2, 99-117

46

Kim, H.1, Lee, H.1, Ahn, J. H.1, An, J., Hong, K. S., Jang, J. G., An, J., Mun, Y. H., Yoo, S. Y., Choi, Y. J., Yun, M. Y., Song, G. Y., Joo, J., Na, D. H.*, Kim, H. N.*, Park, H. H.*, Lee, J. Y.*, Lee, W.* (2021) "Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm", Nano Today, 101149 (IF 20.722, JCR 상위 5%)

* Co-corresponding author

45

Heo, J.1, Choi, J.1, Kim, J. Y., Jeong, H., Choi, D., Han, U., Park, J. H., Park, H. H.*, Hong, J.* (2021) "2D graphene oxide particles induce unwanted loss in pluripotency and trigger early differentiation in human pluripotent stem cells", Journal of Hazardous Materials, 125472 (IF 10.588, JCR 상위 3%)

* Co-corresponding author

44

Park, H. H.1, Kim, H.1, Lee, H.1, Seo, E. U.1, Kim, J. E.1, Lee, J. H., Mun, Y. H., Yoo, S. Y., An, J., Yun, M. Y., Kang, N. W., Kim, D. D., Na, D. H., Hong, K. S., Jang, J. G., Ahn, J. H., Bae, J. S.*, Song, G. Y.*, Lee, J. Y.*, Kim, H. N.*, Lee, W.* (2021) "PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses", Biomaterials, 120827 (IF 12.479, JCR 상위 3%)

43

Lee, S., Lee, J., Byun, H., Kim, S., Joo, J., Park, H. H., Shin, H.* (2021) "Evaluation of the anti-oxidative and ROS scavenging properties of biomaterials coated with epigallocatechin gallate for tissue engineering", Acta Biomaterialia, 124, 166-178

42

Choi, D. W.1, Roh, Y. J.1, Kim, S.1, Lee, H. M., Kim, M., Shin, D., Park, J. H., Park, H. H., Ok, Y. S., Kang, D., Kim, J. H, Tarrago, L., Danial, N. N., Gladyshev, V. N., Min, P. K.*, Lee, B. C.* (2021) "Development of a novel fluorescent biosensor for dynamic monitoring of metabolic methionine redox status in cells and tissues", Biosensors and Bioelectronics, 113031

41

Lee, Y. Y.1, Park, H. H.1, Park, W.1, Kim, H.1, Jang, J. G., Hong, K. S., Lee, J. Y., Seo, H. S., Na, D. H., Kim, T. H., Choy, Y. B., Ahn, J. H.*, Lee, W.*, Park, C. G.* (2021) "Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm" Biomaterials, 267, 120389 (IF 10.317, JCR 상위 3%)

1 Co-first author

40

Cha, H.1, Hong, S.1, Park, J. H.*, Park, H. H.* (2020) "Stem cell-derived exosomes and nanovesicles: Promotion of cell proliferation, migration and anti-senescence for treatment of wound damage and skin ageing", Pharmaceutics, 12, 12, 1135

39

Cha, H.1, Lee, J.1, Park, H. H.*, Park, J., H.* (2020) "Direct conversion of human fibroblasts into osteoblasts triggered by histone deacetylase inhibitor valproic acid", Applied Sciences, 10, 20, 7372

Co-corresponding author

38

Park, H. H.1, Park, W.1, Lee, Y. Y.1, Kim, H., Seo, H. S., Choi, D. W., Kwon, H. K., Na, D. H., Kim, T. H., Choy, Y. B., Ahn, J. H.*, Lee, W.*, Park, C. G.* (2020) "Bioinspired DNase-I-coated melanin-like nanospheres for modulation of infection-associated NETosis dysregulation", Advanced Science, 7, 2001940 (IF 15.840, JCR 상위 5%)

37

Kim, H. N.1, Park, H. H.1, Lim, W.1, Hong, K. S., Ahn, J. H., Na, D. H., Kim, I. S., Jang, J. G.*, Bae, J. S.*, Lee, W.* (2020) "Ferritin nanocage-based methyltransferase SETD6 for COVID-19 therapy", Advanced Functional Materials, 30, 2006110 (IF 16.836, JCR 상위 5%)

1 Co-first author

36

Lee, H.1, Kim, S.1, Yoon, H., Ryu, J., Park, H. H., Hwang, N. S.*, Park, T. H.* (2020) "Intracellular delivery of recombinant RUNX2 facilitated by cell-penetrating protein for the osteogenic differentiation of hMSCs", ACS Biomaterials Science and Engineering, 6, 9, 5202-5214

35

Lee, W.1, Ahn, J. H.1, Park, H. H.1, Kim, H. N.1, Kim, H., Yoo, Y., Shin, H., Hong, K. S., Jang, J. G., Park, C. G., Choi, E. Y. *, Bae, J. S.*, Seo, Y. K.* (2020) "COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm", Signal Transduction and Targeted Therapy, 5, 1, 1-11 (IF 13.493, JCR 상위 3%)

Co-first author

34

Choi, E. Y.1, Park, H. H.1, Kim, H.1, Kim, H., N., Kim, I., Jeon, S., Kim, W.*, Bae, J. S.*, Lee, W.* (2020) "Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for SARS-CoV-2 patients", European Respiratory Journal, 56, 5, 2001531 (IF 12.339, JCR 상위 6%)

Co-first author

33

Park, H., Kwon, M., Kwang Suk Lim*, Park, H. H.* (2020) "Chimeric Antigen Receptor-T cell (CAR-T) therapy targeting hematologic malignancy", KSBB Journal, 35, 3, 183-191

32

Park, H. H.1, Kim, H. N.1, Kim, H.1, Yoo, Y., Shin, H., Choi, E. Y. *, Bae, J. S. *, Lee, W.* (2020) "Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia", Science Advances, 6, 31, eabc1564 (IF 13.117, JCR 상위 5%)

1 Co-first author

31

Yu, H.1, Hong, S.1, Kwon, M., Lee, J., Park, H., H., Lim, K. S.* (2020) "Therapeutic antibodies for the treatment of cancer: Cancer Immunotherapy", KSBB Journal, 35, 2, 105-119

30

Kwon, M., Park, H. H.* (2020) "CAR-T therapy targeting solid tumor", KSBB Journal, 35, 2, 95-104

29

Hong, S.1, Choi, D. W.1, Kim, H. N.1, Park, C. G.*, Lee, W.*, Park, H. H.* (2020) "Protein-based nanoparticles as drug delivery systems", Pharmaceutics, 12, 7, 604

28

Lee, J., Lim, K. S., Park, H. H., Ha, S. J.* (2020) "A qualitative case study on the teaching experiences of biotechnology-related curriculum linked extracurricular program management", The Korean Society of Culture and Convergence, 42, 5, 729-758

27

Hong, S., Park, H. H.* (2020) "Drug delivery system using protein nanoparticles", KSBB Journal, 35, 1, 10-22

26

Ryu, J., Hwang, N. S., Park, H. H.*, Park, T. H.* (2020) "Protein-based direct reprogramming of fibroblasts to neuronal lineage cells", International Journal of Biochemistry and Cell Biology, 121, 105717

Co-corresponding author

25

Lee, J., Park, H. H., Lim, K. S., Lee, H. J., Ha, S. J.* (2019) "A case study on biotechnology-related curriculum linked extracurricular program - focusing on K university CUBE program", KSBB Journal, 34, 4, 359-365

24

Lee, J., Park, H. H., Park, J. H.* (2019) "Efficient production of cell-permeable Oct4 protein using silkworm-originating 30Kc19 protein" Biotechnology and Bioprocess Engineering, 24, 6, 1-8

23

Ryu, J., Park, S. W., Park, H. H.*, Park, T. H.* (2019) "Enhanced single-cell viability using 30Kc6 for efficient expansion of human induced pluripotent stem cells", Process Biochemistry, 78, 161–168

Co-corresponding author

22

Razzak, A., Lee, J. E., Park, H. H., Park, T. H., Choi, S. S.* (2018) "Exploring binding mechanisms between curcumin and silkworm 30Kc19 protein using spectroscopic analyses and computational simulations", Biotechnology and Bioprocess Engineering, 5, 23, 605-616

21

Park, H. H., Triboulet, R., Bentler, M., Guda, S., Du, P., Xu, H., Gregory, R. I., Brendel, C., Williams, D. A.* (2018) "DROSHA knockout leads to enhancement of viral titers for vectors encoding miRNA-adapted shRNAs", Molecular Therapy-Nucleic Acids, 12, 591-599 (IF 7.367, JCR 상위 10%)

20

Park, H. H.1, Woo, W. H.1, Ryu, J., Lee, H. J., Park, J. H.*, Park, T. H.* (2017) "Enzyme delivery using protein-stabilizing and cell-penetrating 30Kc19α protein nanoparticles", Process Biochemistry, 63, 76-83

19

Han, U.1, Park, H. H.1, Kim Y. J. Park, T. H., Park, J. H.*, Hong, J.* (2017) "Efficient encapsulation and sustained release of basic fibroblast growth factor in nanofilm: extension of the feeding cycle of human induced pluripotent stem cell culture", ACS Applied Materials and Interfaces, 9, 30, 25087-25097 (IF 8.758, JCR 상위 10%)

Co-first author

18

Choi, M.1, Park, H. H.1, Choi, D., Han, U., Park, T. H., Lee, H., Park, J. H., Hong, J.* (2017) "Multilayer nanofilms via inkjet printing for stabilizing growth factor and designing desired cell developments", Advanced Healthcare Materials, 6, 14, 1700216 (IF 7.367, JCR 상위 10%)

Co-first author

17

Ryu, J.1, Kim, H.1, Park. H. H., Park, J. H., Lee, H. J., Rhee, W. J., Park, T. H.* (2016) "Protein‐stabilizing and cell‐penetrating properties of α‐helix domain of 30Kc19 protein", Biotechnology Journal, 11, 1443-1451

16

Lee, H. J.1, Park, H. H.1, Sohn, Y., Park, J. H., Ryu, J., Rhee, W. J., Park, T. H.* (2016) "Alpha-galactosidase delivery using 30Kc19-human serum albumin nanoparticles for effective treatment of Fabry disease", Applied Microbiology and Biotechnology, 100, 24, 10395-10402

Co-first author

15

Park, H. H.1, Choi, J.1, Lee, H. J., Park, J. H., Ryu, J., Rhee, W. J.*, Park, T. H.* (2015) "Enhancement of human erythropoietin production in Chinese hamster ovary cells through supplementation of 30Kc19-30Kc6 fusion protein", Process Biochemistry, 50, 6, 973-980

14

Ryu, J., Park. H. H., Park, J. H., Lee, H. J., Rhee, W. J., Park, T. H.* (2016) "Soluble expression and stability enhancement of transcription factors using 30Kc19 cell-penetrating protein", Applied Microbiology and Biotechnology, 100, 3523-3532

13

Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J., Park, T. H.* (2014) "Dimerization of 30Kc19 protein in the presence of amphiphilic moiety and importance of Cys-57 during cell penetration", Biotechnology Journal, 9, 1582-1593

12

Park, J. H.1, Lee, H. J.1, Park, H. H., Rhee, W. J., Park T. H.* (2014) "Stabilization of cellular mitochondrial enzyme complex and sialyltransferase activity through supplementation of 30Kc19 protein", Applied Microbiology and Biotechnology, 99, 2155-2163

11

Park, H. H., Sohn, Y., Yeo, J. W., Park, J. H., Lee, H. J., Ryu, J., Rhee, W. J.*, Park, T. H.* (2014) "Identification and characterization of a novel cell-penetrating peptide of 30Kc19 protein derived from Bombyx mori", Process Biochemistry, 49, 1516-1526

10

Lee, H. J., Park, H. H., Kim, J. A., Park, J. H., Ryu, J., Choi, J., Lee, J., Rhee, W. J., Park, T. H.* (2014) "Enzyme delivery using the 30Kc19 protein and human serum albumin nanoparticles", Biomaterials, 35, 1696-1704

9

Lee, S. H., Rhee, H. -W., Van Noort, D., Lee, H. J., Park, H. H., Shin, I. -S., Hong, J. -I.*, Park, T. H.* (2014) "Microfluidic bead-based sensing platform for monitoring kinase activity", Biosensors and Bioelectronics, 57, 1-9

8

Park, J. H., Park, H. H., Choi, S. S., Park, T. H.* (2012) "Stabilization of enzymes by the recombinant 30Kc19 protein", Process Biochemistry, 47, 164-169

7

Park, J. H., Lee, J. H., Park, H. H., Rhee, W. J., Choi, S. S.*, Park, T. H.* (2012) "A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm”, Biomaterials, 33, 9127-9134

6

Park, J. H., Wang, Z., Jeong, H. -J., Park, H. H., Kim, B. -G., Tan, W. -S., Choi, S. S., Park, T. H.* (2012) "Enhancement of recombinant human EPO production and glycosylation in serum-free suspension culture of CHO cells through expression and supplementation of 30Kc19", Applied Microbiology and Biotechnology, 96, 671-683

5

Wang, Z, Park, J. H., Park, H. H., Tan, W., Park, T. H.* (2011) "Enhancement of recombinant human EPO production and sialylation in Chinese hamster ovary cells through Bombyx mori 30Kc19 gene expression", Biotechnology and Bioengineering, 108, 1634-1642

4

Wang, Z, Park, J. H., Park, H. H., Tan, W., Park, T. H.* (2010) "Enhancement of therapeutic monoclonal antibody production in CHO cells using 30Kc6 gene" Process Biochemistry, 45(12), 1852-1856

3

Park, J. H., Park, H. H., Park, T. H.* (2010) "Cellular engineering for the high-level production of recombinant proteins in mammalian cell systems" Korean Journal of Chemical Engineering, 27(4), 1042-1048

2

Koo, T. Y., Park, J. H., Park, H. H., Park, T. H.* (2009) "Beneficial effect of 30Kc6 gene expression on production of recombinant interferon-β in serum-free suspension culture of CHO cells" Process Biochemistry, 44(2), 146-153

1

Oh, J. S., Park, H. H., Park, T. H.* (2008) "Temperature management strategy for efficient gene expression in a thermally inducible Escherichia coil/bacteriophage system" Biotechnology. and Bioprocess Engineering., 13, 470-475

bottom of page